Company 3 responded to a traffic accident at the 37.6 SB of I-81. Upon arrival, found two vehicles involved. One vehicle had struck the guardrail and rotated up the interstate, losing its engine (found in the median). The second vehicle lost control and rotated. All occupants self-extricated with one treated and transported to the ED. Contained fluids on the road and stood by until wreckers cleared. Call cleared 01:58.